• Infliximab (Remicade), adalimumab (Humira) and golimumab (Simponi): These drugs, called tumor necrosis factor (TNF) inhibitors, or biologics, work by neutralizing a protein produced by your immune system.
• Vedolizumab (Entyvio): This medication is approved for treatment of ulcerative colitis for people who don't respond to or can't tolerate other treatments. It works by blocking inflammatory cells from getting to the site of inflammation.
• Ustekinumab (Stelara). This medication is approved for treatment of ulcerative colitis for people who don't respond to or can't tolerate other treatments. It works by blocking a different protein that causes inflammation.
Other medications:
• Anti-diarrheal medications: For severe diarrhea, loperamide (Imodium A-D) may be effective. Use anti-diarrheal medications with great caution and after talking with your doctor, because they may increase the risk of an enlarged colon (toxic megacolon).
• Pain relievers: For mild pain, your doctor may recommend acetaminophen (Tylenol, others) — but not ibuprofen (Advil, Motrin IB, others), naproxen sodium (Aleve) and diclofenac sodium, which can worsen symptoms and increase the severity of disease.
• Antispasmodics: Sometimes doctors will prescribe antispasmodic therapies to help with cramps.
• Iron supplements: If you have chronic intestinal bleeding, you may develop iron deficiency anemia and be given iron supplements.
Courtesy: Mayo Clinic