Causes, risk factors of Cirrhosis (part 2)

Published : 25 Nov 2021 09:22 PM

A wide range of diseases and conditions can damage the liver and lead to cirrhosis.

• Chronic alcohol abuse

• Chronic viral hepatitis (hepatitis B, C and D)

• Fat accumulating in the liver (nonalcoholic fatty liver disease)

• Iron buildup in the body (hemochromatosis)

• Cystic fibrosis

• Copper accumulated in the liver (Wilson's disease)

• Poorly formed bile ducts (biliary atresia)

• Alpha-1 antitrypsin deficiency

• Inherited disorders of sugar metabolism (galactosemia or glycogen storage disease)

• Genetic digestive disorder (Alagille syndrome)

• Liver disease caused by your body's immune system (autoimmune hepatitis)

• Destruction of the bile ducts (primary biliary cirrhosis)

• Hardening and scarring of the bile ducts (primary sclerosing cholangitis

• Infection, such as syphilis or brucellosis

• Medications, including methotrexate or isoniazid

Risk factors:

Drinking too much alcohol: Excessive alcohol consumption is a risk factor for cirrhosis.

Being overweight: Being obese increases your risk of conditions that may lead to cirrhosis, such as nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.

Having viral hepatitis: Not everyone with chronic hepatitis will develop cirrhosis, but it's one of the world's leading causes of liver disease.

    Courtesy: Mayo Clinic